TBP2 is a general transcription factor specialized for female germ cells.

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Date publication

janvier 2009

Auteurs

Membres identifiés du Cancéropôle Est :
Dr TORA Laszlo


Tous les auteurs :
Muller F, Tora L

Résumé

The complexity of the core promoter transcription machinery has emerged as an additional level of transcription regulation that is used during vertebrate development. Recent studies, including one published in BMC Biology, provide mechanistic insights into how the TATA binding protein (TBP) and its vertebrate-specific paralog TBP2 (TRF3) switch function during the transition from the oocyte to the embryo. See research article http://www.biomedcentral.com/1741-7007/7/45.

Référence

J Biol. 2009;8(11):97