[Methodological aspects on new protocols in oncology]

Date publication

octobre 2008

Auteurs

Membres identifiés du Cancéropôle Est :
Dr LUPORSI Elisabeth

Tous les auteurs :
Luporsi E

Lien Pubmed

http://www.ncbi.nlm.nih.gov/pubmed/19004729

Résumé

This review will summarize specific methodological aspects in targeted therapies like EPR (early progression rate) or RDD (randomized discontinuation design), along with Adaptive Design such as CRM (continual reassessment method, Eff-TOX (dose-finding based on efficacy-toxicity, PPD (predictive probability design) or ADTT (adaptive randomization for targeted therapy) methods.

Référence

Bull Cancer. 2008 Oct;95(10):979-83.