Glycodynamers: Dynamic analogs of arabinofuranoside oligosaccharides
Fiche publication
Date publication
mai 2008
Auteurs
Membres identifiés du Cancéropôle Est :
Pr LEHN Jean-Marie
Tous les auteurs :
Ruff Y, Lehn JM
Lien Pubmed
Résumé
Dynamic analogs of alpha-(1-->5)-D-oligoarabinofuranosides were prepared by oxime polycondensation. These equilibrium polymers were characterized by (1)H NMR studies, NMR DOSY, and MALDI mass spectrometry. Their reversibility under mild acidic conditions was demonstrated by component exchange reaction followed by (1)H NMR studies. Their size and composition can be tuned by component exchange emphasizing their constitutionally dynamic character. They represent dynamic versions of biopolymers, biodynamers.
Référence
Biopolymers. 2008 May;89(5):486-96.