Time to health-related quality of life score deterioration as a modality of longitudinal analysis for health-related quality of life studies in oncology: do we need RECIST for quality of life to achieve standardization?
Fiche publication
Date publication
janvier 2015
Journal
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BORG Christophe, Dr PAGET-BAILLY Sophie, Pr WESTEEL Virginie
Tous les auteurs :
Anota A, Hamidou Z, Paget-Bailly S, Chibaudel B, Bascoul-Mollevi C, Auquier P, Westeel V, Fiteni F, Borg C, Bonnetain F
Lien Pubmed
Résumé
Longitudinal analysis of health-related quality of life (HRQoL) remains unstandardized and compromises comparison of results between trials. In oncology, despite available statistical approaches, results are poorly used to change standards of care, mainly due to lack of standardization and the ability to propose clinical meaningful results. In this context, the time to deterioration (TTD) has been proposed as a modality of longitudinal HRQoL analysis for cancer patients. As for tumor response and progression, we propose to develop RECIST criteria for HRQoL.
Mots clés
Adult, Aged, Breast Neoplasms, drug therapy, Colorectal Neoplasms, drug therapy, Deoxycytidine, analogs & derivatives, Disease Progression, Female, Health Services Needs and Demand, Health Status, Humans, Longitudinal Studies, Middle Aged, Pancreatic Neoplasms, drug therapy, Quality of Life, Response Evaluation Criteria in Solid Tumors
Référence
Qual Life Res. 2015 Jan;24(1):5-18