Feasibility of treating irradiated bone with intramedullary delivered autologous mesenchymal stem cells.
Fiche publication
Date publication
janvier 2011
Journal
Journal of biomedicine & biotechnology
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BRAVETTI Pierre, Pr DOLIVET Gilles, Pr MARIE Pierre-Yves, Pr MERLIN Jean-Louis
Tous les auteurs :
Phulpin B, Dolivet G, Marie PY, Poussier S, Huger S, Bravetti P, Graff P, Merlin JL, Tran N
Lien Pubmed
Résumé
We aimed to explore (i) the short-term retention of intramedullary implanted mesenchymal stem cells BMSCs and (ii) their impact on the bone blood flow and metabolism in a rat model of hindlimb irradiation.
Mots clés
Animals, Antigens, CD, metabolism, Bone Marrow Cells, chemistry, Feasibility Studies, Gamma Rays, Indium, Mesenchymal Stem Cell Transplantation, Mesenchymal Stromal Cells, chemistry, Osteoblasts, chemistry, Radiotherapy, Rats, Rats, Wistar, Regional Blood Flow, Statistics, Nonparametric, Tibia, blood supply, Tomography, Emission-Computed, Single-Photon, Transplantation, Autologous
Référence
J. Biomed. Biotechnol.. 2011 ;2011:560257