Transmission of breast cancer polygenic risk based on single nucleotide polymorphisms.
Fiche publication
Date publication
juin 2018
Journal
Breast (Edinburgh, Scotland)
Auteurs
Membres identifiés du Cancéropôle Est :
Pr PIVOT Xavier
Tous les auteurs :
Cox DG, Heudel PE, Henry J, Pivot X
Lien Pubmed
Résumé
The goal of the present study was to further refine how polygenic risk scores may be used in a large population and to quantify the transmission of risk score through generations.
Mots clés
Alleles, Breast Neoplasms, genetics, Female, Genetic Predisposition to Disease, Humans, Mothers, Multifactorial Inheritance, genetics, Nuclear Family, Polymorphism, Single Nucleotide, genetics, Risk, Risk Assessment
Référence
Breast. 2018 Jun 14;41:14-18