Is histological diagnosis of primary liver carcinomas with fibrous stroma reproducible among experts?
Fiche publication
Date publication
juin 2009
Journal
Journal of clinical pathology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr MALOUF Gabriel
Tous les auteurs :
Malouf G, Falissard B, Azoulay D, Callea F, Ferrell LD, Goodman ZD, Hayashi Y, Hsu HC, Hubscher SG, Kojiro M, Ng IO, Paterson AC, Reynes M, Zafrani ES, Emile JF
Lien Pubmed
Résumé
In the era of targeted therapeutics, histological typing of hepatobiliary carcinomas has major clinical implications. Little is known about the reproducibility of the pathological diagnosis of primary liver carcinomas. Therefore, this study aimed to evaluate the worldwide variation in the pathological expert diagnoses of primary liver carcinomas with fibrous stroma in patients who did not have cirrhosis.
Mots clés
Adolescent, Adult, Aged, Antibodies, analysis, Biomarkers, Tumor, analysis, Carcinoembryonic Antigen, immunology, Carcinoma, Hepatocellular, chemistry, Child, Cholangiocarcinoma, chemistry, Cluster Analysis, Diagnosis, Differential, Female, Hepatocytes, pathology, Humans, Immunohistochemistry, Keratin-19, immunology, Keratin-7, immunology, Keratins, analysis, Liver Neoplasms, chemistry, Male, Medical Oncology, standards, Middle Aged, Reproducibility of Results, Young Adult
Référence
J. Clin. Pathol.. 2009 Jun;62(6):519-24