Chronic Stress protection for postnatal dEpREssioN prEvention (SERENE): a protocol for an exploratory study.

Fiche publication


Date publication

mai 2018

Journal

BMJ open

Auteurs

Membres identifiés du Cancéropôle Est :
Pr SPITZ Elisabeth


Tous les auteurs :
Tharwat D, Trousselard M, Balès M, Sutter-Dallay AL, Fromage D, Spitz E, Dallay D, Harvey T, Welter E, Coatleven F, Cherier L, Teissèdre F, Pouly JL, Dutheil F, Duffaud AM

Résumé

The prevalence of postnatal depression (PND) is significant: reaching up to 20% in the general population. In mechanistic terms, the risk of PND lies in an interaction between a maternal psychophysiological vulnerability and a chronic environmental context of stress. On the one hand, repetition of stressor during pregnancy mimics a chronic stress model that is relevant to the study of the allostatic load and the adaptive mechanisms. On the other hand, vulnerability factors reflect a psychological profile mirroring mindfulness functioning (psychological quality that involves bringing one's complete and non-judgemental attention to the present experience on a moment-to-moment basis). This psychological resource is linked to protective and resilient psychic functioning. Thus, PND appears to be a relevant model for studying the mechanisms of chronic stress and vulnerability to psychopathologies.In this article, we present the protocol of an ongoing study (started in May 2017).

Mots clés

allostatic load, mindfulness, postnatal depression,, stress

Référence

BMJ Open. 2018 May 3;8(5):e018317