Presynaptic inhibition mechanisms may subserve the spinal excitability modulation induced by neuromuscular electrical stimulation.

Fiche publication


Date publication

avril 2018

Journal

Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr LEPERS Romuald


Tous les auteurs :
Grosprêtre S, Gueugneau N, Martin A, Lepers R

Résumé

This study aimed at deciphering the origins of spinal excitability modulation that follows neuromuscular electrical stimulation (NMES). Ten participants (age: 24.6 ± 4.2 years) performed 2 randomized NMES sessions on plantar flexors with frequencies of stimulations of 20 or 100 Hz (pulse width: 1 ms) at 20% of maximal voluntary contraction (MVC). Before and after each session, the posterior tibial nerve was stimulated to record H-reflex of soleus (SOL), gastrocnemius medialis (GM) and gastrocnemius lateralis (GL). D1 presynaptic inhibition was assessed by conditioning H reflex with prior common peroneal nerve stimulation. Resting H-reflex of SOL decreased after both protocols, but in a greater extent following the 100 Hz session (100 Hz: -34.6 ± 7.3%, 20 Hz: -17.1 ± 3.8%; P = 0.002), accompanied by an increase of presynaptic inhibition (+22 ± 5.8% at 100 Hz vs. +8 ± 3.7% at 20 Hz, P < 0.001). GM and GL spinal excitability and presynaptic inhibition were also altered after NMES, but in a similarly extent after 20 Hz and 100 Hz protocols. Neuromuscular fatigue following a single session of NMES involves spinal presynaptic circuitry, even at low stimulation frequency. The spinal sensitivity to NMES seems also muscle dependent.

Mots clés

D1 presynpatic inhibition, Frequency, Gastrocnemius, H-reflex, Neuromuscular fatigue, Soleus, Triceps surae

Référence

J Electromyogr Kinesiol. 2018 Apr 24;40:95-101