Existence of contralateral abnormalities revealed by texture analysis in unilateral intractable hippocampal epilepsy.
Fiche publication
Date publication
décembre 2001
Journal
Magnetic resonance imaging
Auteurs
Membres identifiés du Cancéropôle Est :
Pr NAMER Izzie-Jacques
Tous les auteurs :
Yu O, Mauss Y, Namer IJ, Chambron J
Lien Pubmed
Résumé
We selected 23 patients with unilateral temporal lobe epilepsy characterized by ipsilateral hippocampal sclerosis and an apparently normal contralateral hippocampus on MR imaging. Images were acquired on a 0.28 T MR scanner using a conventional Carr-Purcell Meiboom Gill sequence in all patients and in 9 healthy subjects. Texture analysis was applied to axial MR images of the first and tenth echoes. Texture analysis detects macroscopic lesions and microscopic abnormalities that can not be observed visually. The presence of texture differences in the between normal (controls) and sclerotic hippocampi was ascertained by statistical discriminant analysis. The apparently normal contralateral hippocampi can be classified into three categories in terms of texture: 4 apparently healthy, 8 similar to sclerosis, and 11 different from either healthy or sclerosis. These findings are related to a certain degree of hippocampal alteration, which further investigation might help better characterize.
Mots clés
Adult, Epilepsy, Temporal Lobe, pathology, Hippocampus, pathology, Humans, Magnetic Resonance Imaging
Référence
Magn Reson Imaging. 2001 Dec;19(10):1305-10