Molecular features of Hepatitis E Virus circulation in environmental and human samples.
Fiche publication
Date publication
avril 2018
Journal
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BRONOWICKI Jean-Pierre, Dr JEULIN Hélène
Tous les auteurs :
Fenaux H, Chassaing M, Berger S, Jeulin H, Gentilhomme A, Bensenane M, Bronowicki JP, Gantzer C, Bertrand I, Schvoerer E
Lien Pubmed
Résumé
Hepatitis E virus (HEV) is emerging but its circulation between humans and the environment remains misunderstood. HEV ORF2 gene encodes the capsid playing a key role in viral interactions with surfaces, ORF3 products are involved in the viral cycle. Our aim was to study the molecular characteristics of ORF2 and ORF3 which could favor HEV fitness in patients and the environment.
Mots clés
Hepatitis E virus, Transmission, Ultra-deep sequencing, Variability
Référence
J. Clin. Virol.. 2018 Apr 5;103:63-70