Imaging thrombosis with Tc-labeled RAM.1-antibody in vivo.
Fiche publication
Date publication
mars 2018
Journal
Nuclear medicine and biology
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BRASSE David, Pr LAQUERRIERE Patrice, Dr GACHET Christian
Tous les auteurs :
Ouadi A, Bekaert V, Receveur N, Thomas L, Lanza F, Marchand P, Gachet C, Mangin PH, Brasse D, Laquerriere P
Lien Pubmed
Résumé
Platelets play a major role in thrombo-embolic diseases, notably by forming a thrombus that can ultimately occlude a vessel. This may provoke ischemic pathologies such as myocardial infarction, stroke or peripheral artery diseases, which represent the major causes of death worldwide. The aim of this study was to evaluate the specificity of radiolabeled Rat-Anti-Mouse antibody (RAM.1).
Mots clés
Antibodies, Platelets, Single-photon emission computed tomography, Thrombosis
Référence
Nucl. Med. Biol.. 2018 Mar 17;61:21-27