Evaluation of the new restandardized 25-hydroxyvitamin D assay on the iSYS platform.
Fiche publication
Date publication
février 2018
Journal
Clinical biochemistry
Auteurs
Membres identifiés du Cancéropôle Est :
Pr DUVILLARD Laurence
Tous les auteurs :
Denimal D, Roux S, Duvillard L
Lien Pubmed
Résumé
25-hydroxyvitamin D [25(OH)D] is the most reliable biomarker of vitamin D status, but until now 25(OH)D assays have suffered from inter-laboratory and inter-assay discrepancies. In the setting of the international Vitamin D Standardization Program, Immunodiagnostic Systems (IDS) recently reformulated and restandardized the 25(OH)D immunoassay available on the automated iSYS platform. In the present study, we evaluated this new generation of the 25(OH)D immunoassay (IS-2500).
Mots clés
Biological Assay, methods, Calibration, Chromatography, Liquid, methods, Clinical Laboratory Services, Humans, Immunoassay, methods, Laboratories, Reference Standards, Reproducibility of Results, Sensitivity and Specificity, Tandem Mass Spectrometry, methods, Vitamin D, analogs & derivatives
Référence
Clin. Biochem.. 2018 Feb;52:156-160