Potential added value of a RT-qPCR method of SOX 11 expression, in the context of a multidisciplinary diagnostic assessment of B cell malignancies.
Fiche publication
Date publication
janvier 2018
Journal
Experimental hematology & oncology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr CALLIER Patrick, Dr CASASNOVAS Olivier, Dr FERRAND Christophe, Pr GARNACHE-OTTOU Francine, Dr VERNEREY Dewi
Tous les auteurs :
Magne J, Jenvrin A, Chauchet A, Casasnovas O, Donzel A, Jego L, Aral B, Guy J, Nadal N, Vernerey D, Callier P, Garnache-Ottou F, Ferrand C
Lien Pubmed
Résumé
Expression of SRY [sex-determining region Y]-box11 (SOX11) is specific to mantle cell lymphoma (MCL) and contributes, in conjunction with immunoglobulin variable heavy chain gene mutation status, to the identification of two forms of this disease.
Mots clés
Mantle cell lymphoma, ROC curve analysis-threshold, RT-qPCR-reference genes, SOX11
Référence
Exp Hematol Oncol. 2018 ;7:5