THE TARGETING ABILITY OF FLUORESCENT QUANTUM DOTS TO THE FOLATE RECEPTOR RICH TUMORS.
Fiche publication
Date publication
mars 2019
Journal
Photodiagnosis and photodynamic therapy
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BEZDETNAYA-BOLOTINE Lina, Pr MARCHAL Frédéric
Tous les auteurs :
Mangeolle T, Yakavets I, Lequeux N, Pons T, Bezdetnaya L, Marchal F
Lien Pubmed
Résumé
Quantum dots (QDs) bring new insights in cancer theranostics. Exceptional brightness together with the simple possibility to modify surface with targeting molecules make QDs attractive agents in fluorescence guided surgery and photodynamic therapy. Currently, many targeted QDs have been developed for theranostic purpose. However, their targeting ability was tested mainly in two dimensional monolayer tumor cell models, while our study includes 3D tumor model reflecting the specificity of in vivo tumor environment.
Référence
Photodiagnosis Photodyn Ther. 2019 Mar 15;: