Photopheresis efficacy in the treatment of rheumatoid arthritis: a pre-clinical proof of concept.
Fiche publication
Date publication
septembre 2019
Journal
Journal of translational medicine
Auteurs
Membres identifiés du Cancéropôle Est :
Dr PERRUCHE Sylvain
Tous les auteurs :
Coppard C, Bonnefoy F, Hannani D, Gabert F, Manches O, Plumas J, Perruche S, Chaperot L
Lien Pubmed
Résumé
Despite major advances in rheumatoid arthritis outcome, not all patients achieve remission, and there is still an unmet need for new therapeutic approaches. This study aimed at evaluating in a pre-clinical murine model the efficacy of extracorporeal photopheresis (ECP) in the treatment of rheumatoid arthritis, and to provide a relevant study model for dissecting ECP mechanism of action in autoimmune diseases.
Mots clés
Autoimmunity, Collagen-induced arthritis, Extracorporeal photopheresis, Preclinical study
Référence
J Transl Med. 2019 Sep 18;17(1):312