Genomic Characterization of Renal Cell Carcinoma with Sarcomatoid Dedifferentiation Pinpoints Recurrent Genomic Alterations.
Fiche publication
Date publication
août 2016
Journal
European urology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr MALOUF Gabriel
Tous les auteurs :
Malouf GG, Ali SM, Wang K, Balasubramanian S, Ross JS, Miller VA, Stephens PJ, Khayat D, Pal SK, Su X, Sircar K, Tamboli P, Jonasch E, Tannir NM, Wood CG, Karam JA
Lien Pubmed
Résumé
The genomic features underpinning renal cell carcinoma with sarcomatoid dedifferentiation (sRCC) are not well understood, and at present, there are no specific or effective therapies for sRCC.
Mots clés
Aged, Carcinoma, Renal Cell, genetics, Cyclin-Dependent Kinase Inhibitor p18, genetics, Female, Genes, Neurofibromatosis 2, physiology, Genes, p53, physiology, Humans, Kidney Neoplasms, genetics, Male, Middle Aged, Sequence Analysis, DNA, Statistics as Topic, Von Hippel-Lindau Tumor Suppressor Protein, genetics
Référence
Eur. Urol.. 2016 08;70(2):348-57