Evaluation of paroxysmal nocturnal hemoglobinuria screening by flow cytometry through multicentric interlaboratory comparison in four countries.
Fiche publication
Date publication
décembre 2015
Journal
American journal of clinical pathology
Auteurs
Membres identifiés du Cancéropôle Est :
Dr DEBLIQUIS Agathe, Dr DRENOU Bernard
Tous les auteurs :
Debliquis A, Wagner-Ballon O, Le Garff-Tavernier M, Fossat C, Chatelain B, Letestu R, Drénou B,
Lien Pubmed
Résumé
Paroxysmal nocturnal hemoglobinuria (PNH) is currently diagnosed by flow cytometry; although highly sensitive, its interpretation and reporting appear as critical as its technique. Thus, we developed a quality control scheme for the French-speaking region based on the international recommendations for PNH screening.
Mots clés
Accreditation, Flow cytometry, Interlaboratory comparison, PNH, Robust statistics
Référence
Am. J. Clin. Pathol.. 2015 Dec;144(6):858-68