A rare case of extremely high counts of circulating tumor cells detected in a patient with an oral squamous cell carcinoma.
Fiche publication
Date publication
juillet 2016
Journal
BMC cancer
Auteurs
Membres identifiés du Cancéropôle Est :
Pr DE CARVALHO BITTENCOURT Marcelo, Pr DOLIVET Gilles, Pr FAURE Gilbert, Dr MASTRONICOLA Romina
Tous les auteurs :
Wu X, Mastronicola R, Tu Q, Faure GC, De Carvalho Bittencourt M, Dolivet G
Lien Pubmed
Résumé
Despite aggressive regimens, the clinical outcome of head and neck squamous cell carcinoma remains poor. The detection of circulating tumor cells could potentially improve the management of patients with disseminated cancer, including diagnosis, treatment strategies, and surveillance. Currently, CellSearch(®) is the most widely used and the only Food and Drug Administration-cleared system for circulating tumor cells detection in patients with metastatic breast, colorectal, or prostate cancer. In most cases of head and neck squamous cell carcinoma, only low counts of circulating tumor cells have been reported.
Référence
BMC Cancer. 2016 Jul;16:552