Prognostic value of androgen receptor and FOXA1 co-expression in non-metastatic triple negative breast cancer and correlation with other biomarkers.
Fiche publication
Date publication
juillet 2018
Journal
British journal of cancer
Auteurs
Membres identifiés du Cancéropôle Est :
Dr CHARON-BARRA Céline
Tous les auteurs :
Guiu S, Mollevi C, Charon-Barra C, Boissière F, Crapez E, Chartron E, Lamy PJ, Gutowski M, Bourgier C, Romieu G, Simony-Lafontaine J, Jacot W
Lien Pubmed
Résumé
In luminal androgen receptor (AR) tumours, FOXA1 may direct AR to sites occupied by ER in luminal tumours, thus stimulating proliferation.
Mots clés
Aged, B7-H1 Antigen, genetics, BRCA1 Protein, genetics, Biomarkers, Tumor, genetics, Class I Phosphatidylinositol 3-Kinases, genetics, Disease-Free Survival, Female, Gene Expression Regulation, Neoplastic, genetics, Hepatocyte Nuclear Factor 3-alpha, genetics, Humans, Middle Aged, Mutation, genetics, Neoplasm Recurrence, Local, classification, Prognosis, Receptors, Androgen, genetics, Risk Factors, Triple Negative Breast Neoplasms, classification
Référence
Br. J. Cancer. 2018 07;119(1):76-79