Expression of thrombospondin in non-small cell lung cancer.
Fiche publication
Journal
Anticancer research
Auteurs
Membres identifiés du Cancéropôle Est :
Pr MASCAUX Céline
Tous les auteurs :
Mascaux C, Martin B, Paesmans M, Verdebout JM, Verhest A, Vermylen P, Bosschaerts T, Ninane V, Sculier JP
Lien Pubmed
Résumé
Initially considered as an inhibitor of angiogenesis, the role of thrombospondin is currently controversial. The primary purpose of our study was to determine the expression of thrombospondin (TSP) in invasive lung tumours. The secondary objectives were to investigate its relationship with other factors related to angiogenesis and to assess their clinicopathological significance.
Mots clés
Adult, Aged, Aged, 80 and over, Antibodies, Monoclonal, chemistry, Carcinoma, Non-Small-Cell Lung, blood supply, Female, Humans, Ki-67 Antigen, biosynthesis, Lung Neoplasms, blood supply, Male, Middle Aged, Neovascularization, Pathologic, metabolism, Platelet Endothelial Cell Adhesion Molecule-1, immunology, Survival Rate, Thrombospondins, biosynthesis, Tumor Suppressor Protein p53, biosynthesis
Référence
Anticancer Res.. ;22(2B):1273-7