Focus on Merkel cell carcinoma: diagnosis and staging.

Fiche publication


Date publication

juin 2015

Journal

Skeletal radiology

Auteurs

Membres identifiés du Cancéropôle Est :
Dr HENROT Philippe, Pr TEIXEIRA GONDIM Pedro


Tous les auteurs :
Grandhaye M, Teixeira PG, Henrot P, Morel O, Sirveaux F, Verhaeghe JL, Blum A

Résumé

Merkel cell carcinoma is a rare lymphophilic skin tumor of neuroendocrine origin with the potential for rapid progression. Small, localized lesions are diagnosed and treated clinically, but advanced tumors often undergo imaging evaluation. Due to its rarity, radiologists are unaware of evocative imaging features and usually do not consider Merkel cell carcinoma in the differential diagnosis of soft tissue tumors. Appropriate staging is important to determine appropriate treatment and has an impact on patient prognosis. Multimodality imaging is usually needed, and there is no consensus on the optimal imaging strategy. The purpose of this article is to review various aspects of Merkel cell carcinoma imaging and look in detail at how optimal multimodality staging should be carried out.

Mots clés

Carcinoma, Merkel Cell, pathology, Humans, Magnetic Resonance Imaging, methods, Multimodal Imaging, methods, Neoplasm Staging, Positron-Emission Tomography, methods, Skin Neoplasms, pathology, Tomography, X-Ray Computed, methods

Référence

Skeletal Radiol.. 2015 Jun;44(6):777-86