Time to deterioration in cancer randomized clinical trials for patient-reported outcomes data: a systematic review.

Fiche publication


Date publication

novembre 2019

Journal

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Auteurs

Membres identifiés du Cancéropôle Est :
Pr WORONOFF Macha


Tous les auteurs :
Charton E, Cuer B, Cottone F, Efficace F, Touraine C, Hamidou Z, Fiteni F, Bonnetain F, Woronoff-Lemsi MC, Bascoul-Mollevi C, Anota A

Résumé

The time to deterioration (TTD) approach has been proposed as a modality of longitudinal analysis of patient-reported outcomes (PROs) in cancer randomized clinical trials (RCTs). The objective of this study was to perform a systematic review of how the TTD approach has been used in phase III RCTs to analyze longitudinal PRO data.

Mots clés

Patient-reported outcomes, Randomized clinical trials, Systematic review, Time to deterioration

Référence

Qual Life Res. 2019 Nov 27;: