Noncentrosomal microtubules in C. elegans epithelia.
Fiche publication
Date publication
avril 2016
Journal
Genesis (New York, N.Y. : 2000)
Auteurs
Membres identifiés du Cancéropôle Est :
Dr GALLY Christelle
Tous les auteurs :
Quintin S, Gally C, Labouesse M
Lien Pubmed
Résumé
The microtubule cytoskeleton has a dual contribution to cell organization. First, microtubules help displace chromosomes and provide tracks for organelle transport. Second, microtubule rigidity confers specific mechanical properties to cells, which are crucial in cilia or mechanosensory structures. Here we review the recently uncovered organization and functions of noncentrosomal microtubules in C. elegans epithelia, focusing on how they contribute to nuclear positioning and protein transport. In addition, we describe recent data illustrating how the microtubule and actin cytoskeletons interact to achieve those functions.
Mots clés
Actin Cytoskeleton, metabolism, Animals, Caenorhabditis elegans, cytology, Caenorhabditis elegans Proteins, metabolism, Epithelium, metabolism, Microtubules, metabolism, Protein Transport
Référence
Genesis. 2016 Apr;54(4):229-42