Biomedical applications of laminarin.
Fiche publication
Date publication
mars 2020
Journal
Carbohydrate polymers
Auteurs
Membres identifiés du Cancéropôle Est :
Pr MANO João F.
Tous les auteurs :
Zargarzadeh M, Amaral AJR, Custódio CA, Mano JF
Lien Pubmed
Résumé
The ocean is par excellence a fertile territory of biodiversity on our planet. Marine-derived polysaccharides have been applied as functional materials in biomedicine due to their attractive bioactive properties, safety, high availability and low-cost production. Laminarin (or laminaran), a low molecular weight β-glucan storage polysaccharide present in brown algae, can be (bio-) chemically modified to enhance its biological activity and employed in cancer therapies, drug/gene delivery, tissue engineering, antioxidant and anti-inflammatory functions. This review provides a brief overview on laminarin characteristics, modification strategies and highlights its pivotal biomedical applications.
Mots clés
Anti-tumor, Antioxidant, Beta-glucan, Laminarin, Seaweed, Tissue engineering
Référence
Carbohydr Polym. 2020 Mar 15;232:115774