Neoadjuvant Treatment in Upper Rectal Cancer Does Not Improve Oncologic Outcomes But Increases Postoperative Morbidity.
Fiche publication
Date publication
juin 2020
Journal
Anticancer research
Auteurs
Membres identifiés du Cancéropôle Est :
Pr HEYD Bruno, Dr LAKKIS Zaher
Tous les auteurs :
Tabchouri N, Eid Y, Manceau G, Frontali A, Lakkis Z, Salame E, Lecomte T, Chapet S, Calais G, Heyd B, Karoui M, Alves A, Panis Y, Ouaissi M
Lien Pubmed
Résumé
Neoadjuvant chemoradiation/radiation therapy in locally advanced (LA) upper rectal adenocarcinoma management remains unclear. The aim of this study was to compare outcomes between neoadjuvant chemoradiation therapy (CRT) and upfront surgery (US).
Mots clés
Upper rectal cancer, chemoradiation therapy, long-term functional results, neoadjuvant treatment, recurrence-free and overall survival
Référence
Anticancer Res.. 2020 Jun;40(6):3579-3587