ICG-induced NIR fluorescence mapping in patients with head & neck tumors after the previous radiotherapy.
Fiche publication
Date publication
mai 2020
Journal
Photodiagnosis and photodynamic therapy
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BEZDETNAYA-BOLOTINE Lina, Pr DOLIVET Gilles, Dr LEROUX Agnès, Dr CORTESE Sophie, Dr MASTRONICOLA Romina
Tous les auteurs :
Cortese S, Kerrien E, Yakavets I, Meilender R, Mastronicola R, Renard S, Leroux A, Bezdetnaya L, Dolivet G
Lien Pubmed
Résumé
The distinction between tumor and healthy tissues is complicated in the areas previously subjected to radiation therapy (RT). This is related to the fact that tissues can undergo delayed and irreversible deteriorations such as inflammation, vascular alterations and fibrosis. The trials related to the fluorescence -guided surgery (FSG) in Head and Neck Squamous Cell Carcinoma (HNSCC) patients, previously subjected to RT, have not yet been reported. The present study addresses for the first time the possibilities of tumor near-infrared (NIR) imaging using Indocynaine Green (ICG) in irradiated areas.
Mots clés
Head and neck cancer, Indocyanine green, Irradiated territory, Near-infrared fluorescence imaging, Salvage surgery, Tumor margins
Référence
Photodiagnosis Photodyn Ther. 2020 May 29;:101838