Identification of an oral microbiota signature associated with an impaired orosensory perception of lipids in insulin-resistant patients.
Fiche publication
Date publication
juillet 2020
Journal
Acta diabetologica
Auteurs
Membres identifiés du Cancéropôle Est :
Pr VERGES Bruno
Tous les auteurs :
Besnard P, Christensen JE, Bernard A, Simoneau-Robin I, Collet X, Verges B, Burcelin R
Lien Pubmed
Résumé
Type 2 diabetes leads to multiple sensory dysfunctions affecting notably the gustatory sensitivity. Although this sensory defect, by impacting food choices, might lead to unhealthy eating behavior, underlying mechanisms remains poorly studied. We have recently reported that the composition of microbiota in contact with circumvallate gustatory papillae might affect the orosensory perception of lipids in lean and normoglycemic obese subjects. This finding has prompted us to explore whether such a phenomenon also occurs in diabetic obese patients.
Mots clés
Circumvallate papillae, Lipids, Microbiota, Taste sensitivity, Type 2 diabetes
Référence
Acta Diabetol. 2020 Jul 16;: