Dynamic Covalent Self-Sorting and Kinetic Switching Processes in Two Cyclic Orders: Macrocycles and Macrobicyclic Cages.
Fiche publication
Date publication
août 2020
Journal
Journal of the American Chemical Society
Auteurs
Membres identifiés du Cancéropôle Est :
Pr LEHN Jean-Marie
Tous les auteurs :
Yang Z, Lehn JM
Lien Pubmed
Résumé
Dynamic covalent component self-sorting processes have been investigated for constituents of , macrocycles and macrobicyclic cages based on multiple reversible imine formation. The progressive assembly of the final structures from dialdehyde and polyamine components involved the generation of kinetic products and mixtures of intermediates which underwent component selection and self-correction to generate the final thermodynamic constituents. Importantly, constitutional dynamic networks (CDNs) of macrocycles and macrobicyclic cages were set up either from separately prepared constituents or by in situ assembly from their components. Over time, these CDNs underwent conversion from a kinetically trapped out-of-equilibrium distribution of constituents to the thermodynamically self-sorted one through component exchange in different dimensional orders.
Référence
J. Am. Chem. Soc.. 2020 Aug 18;: