Dehydration of blood platelets by zeodration: in vitro characterization and hemostatic properties in vivo.
Fiche publication
Date publication
septembre 2015
Journal
Transfusion
Auteurs
Membres identifiés du Cancéropôle Est :
Dr GACHET Christian
Tous les auteurs :
Donnet T, Ravanat C, Eckly A, Maurer E, Alame G, Ziessel C, Mangin PH, Freund M, Cazenave JP, Gachet C, Rendu F
Lien Pubmed
Résumé
Platelets (PLTs) are currently stored at room temperature (RT) for 5 to 7 days. So far, there exists no validated method for the preparation and long-term storage of dehydrated PLTs suitable for transfusion after rehydration. In this study, a desiccation process, zeodration, was applied to PLTs.
Mots clés
Animals, Blood Platelets, cytology, Blood Preservation, instrumentation, Desiccation, instrumentation, Hemostasis, Humans, Mice, Platelet Adhesiveness, Thrombin, metabolism
Référence
Transfusion. 2015 Sep;55(9):2207-18