Intravenous Mineralocorticoid Receptor Antagonist Use in Acutely Decompensated Heart Failure with Diuretic Resistance.

Fiche publication


Date publication

janvier 2021

Journal

International heart journal

Auteurs

Membres identifiés du Cancéropôle Est :
Pr ROSSIGNOL Patrick


Tous les auteurs :
Girerd N, Aubry M, Lantelme P, Huttin O, Rossignol P

Résumé

Intravenous mineralocorticoid receptor antagonists (MRAs) have been used in some centers for decades to reduce the risk of hypokalemia and boost diuresis in acutely decompensated heart failure (ADHF). We report the well-tolerated use of intravenous MRAs as a rescue procedure in 3 patients admitted for ADHF with important diuretic resistance. Undertaking trials evaluating the effect of this therapeutic strategy in ADHF could represent a promising avenue.

Mots clés

Cardiac edema, Cardiovascular diseases, Congestive heart failure, Dyspnea, Furosemide, Potassium canrenoate

Référence

Int Heart J. 2021 Jan 16;: