Lactobacillus stress protein GroEL prevents colonic inflammation.

Fiche publication


Date publication

mars 2021

Journal

Journal of gastroenterology

Auteurs

Membres identifiés du Cancéropôle Est :
Dr GARRIDO Carmen, Dr HERMETET François, Pr ORTEGA DEBALLON Pablo, Pr LIRUSSI Frédéric, Dr DEMIDOV Oleg, Pr CHLUBA Johanna, Dr DIAS Alexandre


Tous les auteurs :
Dias AMM, Douhard R, Hermetet F, Regimbeau M, Lopez TE, Gonzalez D, Masson S, Marcion G, Chaumonnot K, Uyanik B, Causse SZ, Rieu A, Hadi T, Basset C, Chluba J, Grober J, Guzzo J, Neiers F, Ortega-Deballon P, Demidov ON, Lirussi F, Garrido C

Résumé

We previously showed that supernatants of Lactobacillus biofilms induced an anti-inflammatory response by affecting the secretion of macrophage-derived cytokines, which was abrogated upon immunodepletion of the stress protein GroEL.

Mots clés

Colonic inflammation, GroEL, IBD (inflammatory bowel disease), Macrophages, Probiotics

Référence

J Gastroenterol. 2021 Mar 29;: