Epithelial to Mesenchymal Transition History: From Embryonic Development to Cancers.
Fiche publication
Date publication
mai 2021
Journal
Biomolecules
Auteurs
Membres identifiés du Cancéropôle Est :
Dr HERVOUET Eric, Dr PEIXOTO Paul
Tous les auteurs :
Lachat C, Peixoto P, Hervouet E
Lien Pubmed
Résumé
Epithelial to mesenchymal transition (EMT) is a process that allows epithelial cells to progressively acquire a reversible mesenchymal phenotype. Here, we recount the main events in the history of EMT. EMT was first studied during embryonic development. Nowadays, it is an important field in cancer research, studied all around the world by more and more scientists, because it was shown that EMT is involved in cancer aggressiveness in many different ways. The main features of EMT's involvement in embryonic development, fibrosis and cancers are briefly reviewed here.
Mots clés
EMT, cancer, development
Référence
Biomolecules. 2021 May 22;11(6):