Cisplatin-based chemoradiation decreases telomerase-specific CD4 TH1 response but increases immune suppressive cells in peripheral blood.
Fiche publication
Date publication
juin 2021
Journal
BMC immunology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr ADOTEVI Olivier, Dr MARTIN Etienne, Dr MIRJOLET Céline, Dr VULQUIN Noémie, Dr BOUSTANI Jihane
Tous les auteurs :
Boustani J, Joseph ELM, Martin E, Benhmida S, Lecoester B, Tochet F, Mirjolet C, Chevalier C, Thibouw D, Vulquin N, Servagi S, Sun X, Adotévi O
Lien Pubmed
Résumé
The synergistic effect of chemoradiation (CRT) has been previously demonstrated in several cancer types. Here, we investigated the systemic immune effects of CRT in patients with lung or head and neck cancer.
Mots clés
Chemoradiation, Immune suppressive cells, Tumor-specific T cell response
Référence
BMC Immunol. 2021 Jun 18;22(1):38