Under-recognized toxicities of cranial irradiation.
Fiche publication
Date publication
juillet 2021
Journal
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
Auteurs
Membres identifiés du Cancéropôle Est :
Pr ANTONI Delphine
Tous les auteurs :
Le Guyader M, Antoni D
Lien Pubmed
Résumé
Cranial irradiation of primary or metastatic lesions is frequent, historically with 3D-conformal radiation therapy and now with stereotactic radiosurgery and intensity modulation. Evolution of radiotherapy technique is concomitant to systemic treatment evolution permitting long time survival. Thus, physicians have to face underestimated toxicities on long-survivor patients and unknown toxicities from combination of cranial radiotherapy to new therapeutics as targeted therapies and immunotherapies. This article proposes to develop these toxicities, without being exhaustive, to allow a better apprehension of cranial irradiation in current context.
Mots clés
Alopecia, Alopécie, Brain irradiation, Cognition, Cognitive impairments, Irradiation encéphalique, Smart syndrome, Xerostomia, Xérostomie
Référence
Cancer Radiother. 2021 Jul 14;: