Pharmacokinetics of oral vinorelbine in French children with recurrent or progressive primary low-grade glioma.
Fiche publication
Date publication
octobre 2021
Journal
British journal of clinical pharmacology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr CHASTAGNER Pascal, Pr ENTZ-WERLE Natacha
Tous les auteurs :
Hamimed M, Gattacceca F, André N, Tresch-Bruneel E, Probst A, Chastagner P, Pagnier A, De Carli E, Entz-Werlé N, Grill J, Aerts I, Frappaz D, Bertozzi-Salamon AI, Solas C, Leblond P
Lien Pubmed
Résumé
There is a crucial need for pharmacokinetic (PK) data of oral vinorelbine (VNR) in pediatric population. The aim of this work was to assess the PK profile of orally administered VNR in children with recurrent/progressive primary low-grade glioma (LGG).
Mots clés
Low-grade glioma, between subject variability, exposure matching, non-compartmental analysis, pediatrics, pharmacokinetics, vinorelbine
Référence
Br J Clin Pharmacol. 2021 Oct 28;: