Five Functional Aspects of the Epidermal Barrier.
Fiche publication
Date publication
octobre 2021
Journal
International journal of molecular sciences
Auteurs
Membres identifiés du Cancéropôle Est :
Pr AUBIN François
Tous les auteurs :
Lefèvre-Utile A, Braun C, Haftek M, Aubin F
Lien Pubmed
Résumé
The epidermis is a living, multilayered barrier with five functional levels, including a physical, a chemical, a microbial, a neuronal, and an immune level. Altogether, this complex organ contributes to protect the host from external aggression and to preserve its integrity. In this review, we focused on the different functional aspects.
Mots clés
ceramides, desmosomes, epidermis, immunity, keratinization, microbiome, sensory nerves, skin barrier, stratum corneum, tight junctions
Référence
Int J Mol Sci. 2021 Oct 28;22(21):