Selective Internal Radiation Combined with Chemotherapy Maintains the Quality of Life in Intrahepatic Cholangiocarcinomas.

Fiche publication


Date publication

novembre 2021

Journal

Current oncology (Toronto, Ont.)

Auteurs

Membres identifiés du Cancéropôle Est :
Pr AYAV Ahmet


Tous les auteurs :
Goislard de Monsabert C, Touchefeu Y, Guiu B, Campillo-Gimenez B, Farges O, Tougeron D, Baumgaertner I, Ayav A, Beuzit L, Pracht M, Lièvre A, Le Sourd S, Boudjema K, Rolland Y, Garin E, Boucher E, Edeline J

Résumé

In the Yttrium-90 Microspheres in Cholangiocarcinoma (MISPHEC) single-arm phase 2 trial, concomitant chemotherapy and selective internal radiotherapy (SIRT) showed antitumor activity as a first-line treatment of unresectable intrahepatic cholangiocarcinomas (ICCs). In this sub-analysis, we aimed to evaluate one of the secondary endpoints, the health-related quality of life (QoL), evaluated with an EORTC QLQ-C30 instrument at the baseline and during treatment.

Mots clés

Yttrium-90, biliary tract cancer, chemotherapy, patient-reported outcomes, radioembolization

Référence

Curr Oncol. 2021 Nov 8;28(6):4530-4541