N-Acetyl Cysteine Restores Limb Function, Improves Mitochondrial Respiration, and Reduces Oxidative Stress in a Murine Model of Critical Limb Ischaemia.

Fiche publication


Date publication

novembre 2018

Journal

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

Auteurs

Membres identifiés du Cancéropôle Est :
Pr GENY Bernard


Tous les auteurs :
Lejay A, Paradis S, Lambert A, Charles AL, Talha S, Enache I, Thaveau F, Chakfe N, Geny B

Résumé

The aim of this study was to investigate whether antioxidant therapy might decrease oxidative stress related deleterious effects in the setting of critical limb ischaemia (CLI).

Mots clés

Ischaemia reperfusion, N-acetyl cysteine, Peripheral arterial disease

Référence

Eur J Vasc Endovasc Surg. 2018 Nov;56(5):730-738