Temporal trends in initiation of mineralocorticoid receptor antagonists and risk of subsequent withdrawal in patients with heart failure: A nationwide study in Denmark from 2003-2017.
Fiche publication
Date publication
décembre 2021
Journal
European journal of heart failure
Auteurs
Membres identifiés du Cancéropôle Est :
Pr ROSSIGNOL Patrick
Tous les auteurs :
Zahir D, Bonde A, Madelaire C, Malmborg M, Butt JH, Fosbol E, Gislason G, Torp-Pedersen C, Andersson C, Rossignol P, McMurray JJV, Kober L, Schou M
Lien Pubmed
Résumé
Despite landmark heart failure (HF) with reduced ejection fraction (HFrEF) trials showing effect of Mineralocorticoid Receptor Antagonists (MRA) on the risk of death and HF hospitalization, it has been suggested that MRAs are underutilized or frequently withdrawn. This study sought to identify temporal trends in the initiation of MRAs and the subsequent risk of withdrawal and adherence of MRAs in HF patients treated with a renin-angiotensin system inhibitor and a beta-blocker in Denmark from 2003-2017.
Mots clés
adherence, heart failure, pharmacotherapy
Référence
Eur J Heart Fail. 2021 Dec 30;: