[Tridimensional in vitro models of nervous and immune systems in the skin].
Fiche publication
Date publication
janvier 2021
Journal
Medecine sciences : M/S
Auteurs
Membres identifiés du Cancéropôle Est :
Dr FLACHER Vincent
Tous les auteurs :
Muller Q, Berthod F, Flacher V
Lien Pubmed
Résumé
The immune system and the sensory nervous system are responsible for perceiving danger under distinct yet complementary forms. In the last few years, neuroimmune interactions have become an important topic of dermatological research for conditions including wound healing, atopic dermatitis and psoriasis. We present here a selection of tridimensional in vitro models that reproduce skin structure and integrate an immune or a sensory function. Future evolutions of such models are expected to greatly contribute in a better understanding of reciprocal influences between sensory nervous system and immune system.
Mots clés
Animals, Cells, Cultured, Humans, Models, Biological, Neuroimmunomodulation, physiology, Organ Culture Techniques, Skin, immunology, Tissue Culture Techniques, methods, Tissue Engineering, methods, Tissue Scaffolds, Wound Healing, physiology
Référence
Med Sci (Paris). 2021 Jan;37(1):68-76