Pay attention to the basal ganglia: a volumetric study in early dementia with Lewy bodies.
Fiche publication
Date publication
décembre 2019
Journal
Alzheimer's research & therapy
Auteurs
Membres identifiés du Cancéropôle Est :
Dr NOBLET Vincent
Tous les auteurs :
Botzung A, Philippi N, Noblet V, Loureiro de Sousa P, Blanc F
Lien Pubmed
Résumé
Cortical and subcortical cognitive impairments are usually found in dementia with Lewy bodies (DLB). Roughly, they comprise visuo-constructive/executive function and attention/processing speed impairments, whereas memory would remain relatively spared. In this study, we focused on the neuro-anatomical substrates of attention and processing speed, which is still poorly understood. For the purpose of the study, we examined the correlations between behavioral scores measuring the speed of processing and the degree of cerebral atrophy in patients with prodromal to moderate DLB.
Mots clés
Attention, Basal ganglia, Dementia with Lewy bodies, MRI, Mild cognitive impairment, Neuroimaging, Processing speed, Prodromal, VBM
Référence
Alzheimers Res Ther. 2019 12 21;11(1):108