Dendronized oligoethylene glycols with phosphonate for cell-repellent coating of oxide surfaces: coarse-scale and nanoscopic interfacial forces.
Fiche publication
Date publication
mai 2021
Journal
RSC advances
Auteurs
Membres identifiés du Cancéropôle Est :
Dr FELDER-FLESCH Delphine
Tous les auteurs :
Czajor J, Abuillan W, Nguyen DV, Heidebrecht C, Mondarte EA, Konovalov OV, Hayashi T, Felder-Flesch D, Kaufmann S, Tanaka M
Lien Pubmed
Résumé
Dendronized oligoethylene glycols (dendron OEGs) with two phosphonate groups (phosphonate ) have been drawing significant attention as a new class of coating materials for superparamagnetic iron oxide surfaces. However, despite dendron OEGs showing outstanding stability in physiological fluids in previous studies, little is understood about their structure and mechanical properties. Herein we report the surface and internal structures and mechanical properties of dendron OEGs, and quantitatively determine their ability to avoid non-specific adhesion of blood platelets. To gain insight into the interfacial force interactions, we measured the coarse-scale surface force acting on cell-sized particles and mapped the nanoscopic pinning centers by fast force mapping.
Référence
RSC Adv. 2021 May 13;11(29):17727-17733