Optimal timing of interval debulking surgery for advanced epithelial ovarian cancer: A retrospective study from the ESME national cohort.

Fiche publication


Date publication

août 2022

Journal

Gynecologic oncology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr MARCHAL Frédéric


Tous les auteurs :
Thomas QD, Boussere A, Classe JM, Pomel C, Costaz H, Rodrigues M, Ray-Coquard I, Gladieff L, Rouzier R, Rouge TM, Gouy S, Barranger E, Sabatier R, Floquet A, Marchal F, Guillemet C, Polivka V, Martin AL, Colombo PE, Fiteni F

Résumé

Interval debulking surgery is recommended after 3-4 cycles (standard IDS) of neoadjuvant chemotherapy (NACT) for epithelial ovarian cancer (EOC) not able to received upfront complete debulking surgery. However, real world practices frequently report performing IDS after ≥5 NAC cycles (delayed IDS). The aim of this work was to evaluate the impact on survival of the number of NACT cycles before IDS.

Mots clés

Cytoreduction, Neoadjuvant, Prognosis, Propensity score, Survival

Référence

Gynecol Oncol. 2022 08 12;: