Carissa edulis Vahl (Apocynaceae) extract, a medicinal plant of Benin pharmacopoeia, induces potent endothelium-dependent relaxation of coronary artery rings involving nitric oxide.
Fiche publication
Date publication
août 2022
Journal
Phytomedicine : international journal of phytotherapy and phytopharmacology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr SCHINI-KERTH Valérie, Dr HEINTZ Dimitri, Dr AUGER Cyril
Tous les auteurs :
Hounguè U, Villette C, Tokoudagba JM, Chaker AB, Remila L, Auger C, Heintz D, Gbaguidi FA, Schini-Kerth VB
Lien Pubmed
Résumé
Hypertension is a major cardiovascular risk factor that affects most countries including those of Africa. Although Carissa edulis Vahl, Diodia scandens Sw. and Cleome gynandra L. are traditionally used in Benin as antihypertensive treatments with some efficacy mentioned by the local population, their biological activity on the cardiovascular system remains poorly studied.
Mots clés
Carissa edulis, Endothelium, Hypertension, Nitric oxide, Vasorelaxant activity
Référence
Phytomedicine. 2022 08 5;105:154370