Assessment of plasma Catestatin in COVID-19 reveals a hitherto unknown inflammatory activity with impact on morbidity-mortality.

Fiche publication


Date publication

septembre 2022

Journal

Frontiers in immunology

Auteurs

Membres identifiés du Cancéropôle Est :
Dr GOUMON Yannick


Tous les auteurs :
Schneider F, Le Borgne P, Herbrecht JE, Danion F, Solis M, Hellé S, Betscha C, Clere-Jehl R, Lefebvre F, Castelain V, Goumon Y, Metz-Boutigue MH

Résumé

Neuroendocrine cells release Catestatin (CST) from Chromogranin A (CgA) to regulate stress responses. As regards COVID-19 patients (COVID+) requiring oxygen supply, to date nobody has studied CST as a potential mediator in the regulation of immunity.

Mots clés

COVID, Catestatin, Chromogranin A, Innate immunity, critically ill, hypoxia, nosocomial disease

Référence

Front Immunol. 2022 09 29;13:985472