Gene-expression analysis of cementoblasts and osteoblasts.
Fiche publication
Date publication
juin 2016
Journal
Journal of periodontal research
Auteurs
Membres identifiés du Cancéropôle Est :
Dr ROEDER Emilie
Tous les auteurs :
Matthews BG, Roguljic H, Franceschetti T, Roeder E, Matic I, Vidovic I, Joshi P, Kum KY, Kalajzic I
Lien Pubmed
Résumé
Cementum and bone are similar mineralized tissues, but cementum accumulates much more slowly than bone, does not have vasculature or innervation and does not undergo remodeling. Despite these differences, there are no well-established markers to distinguish cementoblasts from other mature mineralizing cells such as osteoblasts and odontoblasts. The purpose of this study was to assess differences in gene expression between cementoblasts and osteoblasts using gene profiling of cell populations isolated directly from osteocalcin-green fluorescent protein (OC-GFP) transgenic mice.
Mots clés
Wnt signaling pathway, cementoblast, gene expression, osteoblast, osteocalcin
Référence
J Periodontal Res. 2016 06;51(3):304-12