An incidental finding of maternal multiple myeloma by non invasive prenatal testing.
Fiche publication
Date publication
décembre 2017
Journal
Prenatal diagnosis
Auteurs
Membres identifiés du Cancéropôle Est :
Dr DORVAUX Véronique
Tous les auteurs :
Imbert-Bouteille M, Chiesa J, Gaillard JB, Dorvaux V, Altounian L, Gatinois V, Mousty E, Finge S, Bourquard P, Vermeesch JR, Legius E, Vandenberghe P
Lien Pubmed
Résumé
What is already known about this subject? Non invasive prenatal testing for fetal trisomies 13, 18, and 21 occasionally identifies maternal cancer. What does this study add? A further case of maternal cancer incidentally diagnosed by routine NIPT. Extensive NIPT abnormalities are unlikely to be of fetal origin. Information given to patients should also adequately advise patients on potential incidental findings and might offer the option to opt out of receiving results beyond the trisomy report. International guidelines would improve patient counseling.
Mots clés
Adult, Female, Genetic Testing, Humans, Incidental Findings, Maternal Serum Screening Tests, Multiple Myeloma, diagnosis, Pregnancy, Pregnancy Complications, Neoplastic, diagnosis, Sequence Analysis, DNA
Référence
Prenat Diagn. 2017 12;37(12):1257-1260