Acute skin toxicity of conventional fractionated versus hypofractionated radiotherapy in breast cancer patients receiving regional node irradiation: the real-life prospective multicenter HYPOBREAST cohort.
Fiche publication
Date publication
décembre 2022
Journal
BMC cancer
Auteurs
Membres identifiés du Cancéropôle Est :
Dr CLAVIER Jean-Baptiste, Dr DESANDES Emmanuel, Dr GUIHARD Sébastien, Pr PEIFFERT Didier, Dr FAIVRE Jean-Christophe
Tous les auteurs :
Bruand M, Salleron J, Guihard S, Crety CM, Liem X, Pasquier D, Lamrani-Ghaouti A, Charra-Brunaud C, Peiffert D, Clavier JB, Desandes E, Faivre JC
Lien Pubmed
Résumé
Large-scale trials have shown that hypofractionated adjuvant breast radiotherapy was as effective in terms of survival and local control as conventional fractionated radiotherapy, and acute toxicity was reduced with hypofractionated radiotherapy. However, there is a lack of data about the toxicity of breast with regional nodal irradiation (RNI). The aim of this study was to assess the effect of fractionation on radiation-related acute skin toxicity in patients receiving RNI in addition to whole-breast or chest wall irradiation, using real-life data.
Mots clés
Adjuvant radiotherapy, Breast neoplasms, Conformal radiotherapy, Hypofractionation, Intensity-modulated, Observational study, Prospective studies, Radiation dose, Radiotherapy, Radiotherapy dose fractionation
Référence
BMC Cancer. 2022 12 16;22(1):1318