Persistent deficiency of mucosal-associated invariant T cells during dermatomyositis.
Fiche publication
Date publication
septembre 2020
Journal
Rheumatology (Oxford, England)
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BENSUSSAN Armand
Tous les auteurs :
Cassius C, Branchtein M, Battistella M, Amode R, Lepelletier C, Jachiet M, de Masson A, Frumholtz L, Chasset F, Amoura Z, Mathian A, Samri A, Monfort JB, Bachmeyer C, Bengoufa D, Cordoliani F, Bagot M, Bensussan A, Bouaziz JD, Le Buanec H
Lien Pubmed
Résumé
Mucosal-associated invariant T (MAIT) cells are innate-like lymphocytes that are important for antibacterial immunity and may have regulatory roles. MAIT cells are decreased during SLE. However, their frequencies and phenotype have not been investigated in DM. We studied MAIT cell frequencies and phenotype in DM patients with active and inactive disease (after treatment).
Mots clés
T-lymphocytes, autoimmunity, dermatomyositis, immunology, mucosal-associated invariant T cells
Référence
Rheumatology (Oxford). 2020 09 1;59(9):2282-2286